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Raltegravir potassium salt
CAS No. 871038-72-1
Raltegravir potassium salt ( MK0518 potassium salt;MK-0518 potassium salt;MK 0518 potassium salt )
Catalog No. M16328 CAS No. 871038-72-1
A potent, selective, orally bioavailable HIV-integrase inhibitor with IC50 of 15 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 31 | In Stock |
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| 25MG | 55 | In Stock |
|
| 50MG | 87 | In Stock |
|
| 100MG | 160 | In Stock |
|
| 200MG | 241 | In Stock |
|
| 500MG | 408 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameRaltegravir potassium salt
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NoteResearch use only, not for human use.
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Brief DescriptionA potent, selective, orally bioavailable HIV-integrase inhibitor with IC50 of 15 nM.
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DescriptionA potent, selective, orally bioavailable HIV-integrase inhibitor with IC50 of 15 nM; essentially inactive (IC50s>50 uM) against HCV Pol, HIV RT, HIV RNase-H, and human α/β/γ Pol; shows inhibitory activity against the wild type virus and a selection of mutants; the first HIV-integrase inhibitor for the treatment of HIV-1 infection.HIV Infection Approved
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SynonymsMK0518 potassium salt;MK-0518 potassium salt;MK 0518 potassium salt
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PathwayMicrobiology/Virology
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TargetHIV
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RecptorHIV;Integrase(IN)
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Research AreaInfection
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IndicationHIV Infection
Chemical Information
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CAS Number871038-72-1
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Formula Weight482.51
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Molecular FormulaC20H20FKN6O5
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESCC1=NN=C(O1)C(=O)NC(C)(C)C2=NC(=C(C(=O)N2C)[O-])C(=O)NCC3=CC=C(C=C3)F.[K+]
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Chemical Name4-Pyrimidinecarboxamide, N-[(4-fluorophenyl)methyl]-1,6-dihydro-5-hydroxy-1-methyl-2-[1-methyl-1-[[(5-methyl-1,3,4-oxadiazol-2-yl)carbonyl]amino]ethyl]-6-oxo-, potassium salt(1:1)
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Summa V, et al. J Med Chem. 2008 Sep 25;51(18):5843-55.
2. Malet I, et al. Antimicrob Agents Chemother. 2008 Apr;52(4):1351-8.
3. Cooper DA, et al. N Engl J Med. 2008 Jul 24;359(4):355-65.
2. Malet I, et al. Antimicrob Agents Chemother. 2008 Apr;52(4):1351-8.
3. Cooper DA, et al. N Engl J Med. 2008 Jul 24;359(4):355-65.
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